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Filtered Search Results
Medchemexpress LLC Methoxy-PEG3 tosylate | 62921-74-8 | MFCD13184964 | 98.8% | 318.39 g/mol | C14H22O6S | 250 MG
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m-PEG3-Tos is a methoxy-terminated PEG3 tosylate used as a short, flexible PEG linker and intermediate in small-molecule synthesis. It provides three ethylene glycol units with a tosylate leaving group, making it suitable for nucleophilic substitution to install PEG chains and build PROTAC linkers or other conjugates.
- Provides three ethylene glycol units for short, flexible spacing.
- Contains a tosylate leaving group suitable for nucleophilic substitution.
- High purity (98.75%) appropriate for synthetic applications.
- Available in small-scale quantities for research use, such as 250 mg.
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Medchemexpress LLC (S,R,S)-AHPC-PEG3-NH2 | 2010159-56-3 | MFCD31727698 | 99.3% | 619.80 g/mol | C30H45N5O7S | 500 MG
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(S,R,S)-AHPC-PEG3-NH2 is a VHL E3 ligase ligand-linker conjugate terminating in a primary amine. It is supplied as a research-grade powder for use as a building block in PROTAC synthesis and related chemical biology applications.
- VHL-binding motif for targeted protein degradation studies.
- Three-unit PEG linker with terminal amine for facile conjugation.
- High purity suitable for synthetic applications.
- Supplied as a powder convenient for storage and handling.
- Store and handle per the manufacturer's datasheet recommendations.
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Medchemexpress LLC Aminooxy-PEG3-acid | 1807540-79-9 | 95.0% | 237.25 | 100 MG
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Aminooxy-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Calcein (tetraethyl ester) | 1170856-93-5 | 99.5% | 100 MG
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Calcein tetraethyl ester is a fluorescent dye used in biology for testing cell viability and short-term cell labeling. It can be transported through the cellular membrane into live cells.
- Molecular weight: 734.75
- Formula: C38H42N2O13
- Appearance: Solid
- Color: Light yellow to yellow
- Emission (Em): 515
- Excitation (Ex): 489
- Solubility in DMSO: 25 mg/mL
- Insolubility in H2O: < 0.1 mg/mL
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Medchemexpress LLC THP-PEG3-OH | 60221-37-6 | 98.7% | 5 G
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THP-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
- Can be used in the synthesis of PROTACs
- Contains two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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Medchemexpress LLC THP-PEG3-OH | 60221-37-6 | 98.7% | 1 G
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THP-PEG3-OH is a PEG-based PROTAC linker used in the synthesis of PROTACs. This compound is intended for research use only and is not sold to patients.
- Enables the synthesis of PROTACs
- Functions as a PROTAC linker
- Utilizes the PROTAC pathway
- Facilitates selective degradation of target proteins via the ubiquitin-proteasome system
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Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 TFA (cereblon ligand-linker conjugates 5 TFA) | 2414913-97-4 | 99.0% | 500 MG
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Pomalidomide-PEG3-C2-NH2 TFA is a synthetic E3 ligase ligand-linker conjugate. It is composed of a pomalidomide-based cereblon ligand and a 3-unit PEG linker.
- Comprises a pomalidomide-based cereblon ligand.
- Includes a 3-unit PEG linker.
- Can be used for the synthesis of PROTACs.
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Medchemexpress LLC Tos-PEG5-Boc | 581065-94-3 | ≥97.0% | 1 G
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Tos-PEG5-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. These compounds consist of two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other targeting the protein intended for degradation. PROTACs leverage the intracellular ubiquitin-proteasome system for selective protein degradation.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Molecular weight: 476.58
- Chemical formula: C22H36O9S
- Appears as a viscous liquid
- Colorless to light yellow
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Medchemexpress LLC (S,R,S)-AHPC-C6-PEG3-C4-Cl | 1835705-55-9 | MFCD31560478 | >95.0% | 751.42 g/mol | C38H59ClN4O7S | 2 G
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(S,R,S)-AHPC-C6-PEG3-C4-Cl is a VHL E3 ligase ligand-linker conjugate used as a building block for PROTAC design and targeted protein degradation research. It combines a stereodefined AHPC VHL ligand with a mixed C6-PEG3-C4 linker and has been used in cell-based assays to induce degradation of HaloTag fusion proteins.
- Used as a VHL E3 ligase ligand building block for PROTAC synthesis.
- Soluble in DMSO at 100 mg/mL (may require ultrasonication).
- Suitable for in vivo formulations at ≥2.5 mg/mL in recommended cosolvent systems.
- Stable in pure form when stored at -20°C for extended periods.
- Molecular weight 751.42 g/mol and molecular formula C38H59ClN4O7S.
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Medchemexpress LLC Amino-PEG3-C2-azido | 134179-38-7 | MFCD00269874 | 99.7% | 218.25 g/mol | C8H18N4O3 | 500 MG
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Amino-PEG3-C2-azido is a PEG-based PROTAC linker and click-chemistry reagent containing an azide functional group. It enables copper-catalyzed and strain-promoted azide-alkyne cycloaddition for conjugation of azide- and alkyne-bearing fragments, making it suitable for linker assembly in degrader synthesis and bioconjugation workflows.
- High purity (99.67%) suitable for synthetic applications.
- Azide functionality enables CuAAC and SPAAC conjugations.
- Compatible with assembly of PROTAC linkers and bioconjugates.
- Molecular weight 218.25 g/mol; formula C8H18N4O3.
- Available in multiple pack sizes to support small- and larger-scale work.
- Store at -20°C, protect from light, under inert gas for stability.
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Medchemexpress LLC Azido-PEG5-alcohol | 86770-68-5 | >97.0% | 263.29 g/mol | C10H21N3O5 | 25 G
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Azido-PEG5-alcohol is an azide-terminated polyethylene glycol (PEG) linker containing five ethylene glycol units that is used as a click-chemistry reagent and as a linker in bioconjugation workflows. It participates in copper-catalyzed and strain-promoted azide-alkyne cycloaddition reactions and is supplied for research use only.
- Azide functional group for click chemistry
- Five-unit PEG spacer adds hydrophilicity and flexibility
- Suitable for antibody-drug conjugate and PROTAC linker synthesis
- Characterized by NMR and LC-MS, purity >97.0%
- Available in multiple package sizes, including 25 G
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Medchemexpress LLC Azido-PEG5-azide | 356046-26-9 | 99.98% | 332.36 | 500 MG
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Azido-PEG5-azide is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a versatile click chemistry reagent, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC M-PEG3-succinimidyl carbonate | 477775-77-2 | 99.4% | C12H19NO8 | 250 MG
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m-PEG3-succinimidyl carbonate is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker: one binds to an E3 ubiquitin ligase, and the other to the target protein. These molecules function by utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules m-PEG3-triethoxysilane | 2243566-45-0 | | 1g
Broadpharm | m-PEG3-triethoxysilane | 1g | 411413983 | BP-24075 | 98.000 | 2243566-45-0 | | 395.568 | C17H37NO7Si
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Medchemexpress LLC MEDCHEMEXPRESS LLC
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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5000757385 SODIUM SELENIDE 25MG
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